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卓怡孜主任 / 卓怡孜主任

最高學歷:國立中山大學化學系博士

專長:質譜分析、化妝品檢驗、分析化學、儀器分析

授課科目:化妝品檢驗、化妝品檢驗實驗、有機化學、化學、進階化學、化妝品分析化學、儀器分析、化妝品生化科技

電話分機:1100

電子信箱:

ytcho@ms.yuhing.edu.tw

  • 國立中山大學化學系博士

  • 國立交通大學應用化學所碩士

  • 國立交通大學應用化學系學士

  • 產業科技發展協進會助理研究員 (1996/08 ~ 1997/08)

  • 高雄市私立育英護校教師 (1999/08 ~ 2003/07)

  • 育英醫護管理專科學校講師 (2003/08 ~ 2011/08)

  • 育英醫護管理專科學校助理教授 (2011/09 ~2016/09)

  • 育英醫護管理專科學校副教授 (2016/10 ~2023/07)

  • 育英醫護管理專科學校教授 (2023/08 ~迄今)

  • 育英醫護管理專科學校資圖處主任兼教務處副主任  (2011/08 ~ 2012/07)

  • 育英醫護管理專科學校代理校長(2023/02 ~2023/07)

  • 育英醫護管理專科學校教務處主任 (2012/08 ~迄今)

 

  • 質譜分析

  • 化妝品檢驗

  • 分析化學

  • 儀器分析

  • 教授證書

  • 校化學及理化

一、期刊論文

  •  Yi. T. Cho,* H. Su, C. Y. Wu, J. Jeng, C. W. Lee, D. C. Wu, T. L. Huang, J. Shiea* 2022 “The Study of Distribution of Ingested Terbinafifine on Skin with Ambient Ionization Tandem Mass Spectrometry” J. Food Drug Anal. 30, 2 , 303-315 (SCI, IF=6.157)

  • Yi. T. Cho,* H. Su, C. Y. Wu, T. L. Huang, J. Jeng, M. Z. Huang, D. C. Wu, J. Shiea* 2021 “Molecular Mapping of Sebaceous Squalene by Ambient Mass Spectrometry” Anal. Chem. 93, 16608−16617 (SCI, IF=8.008)

  •  H. Su, T. L. Huang, C. T. Chi, Yi. T. Cho, C. W. Lee, J. Jeng, J. Shiea* 2021 “Molecular cartography of residue pesticides on grape surface in 3D by ambient ionization tandem mass spectrometry”J. Food Drug Anal. 29, 4 , 751-763 (SCI, IF=6.157)

  •  J. Jeng,* Z. H. Jiang, Y. T. Cho , H. Su, C. W. Lee, J. Shiea* 2020 “Obtaining Molecular Imagings of Pesticide Residues on Strawberry Surfaces with Probe Sampling Followed by Ambient Ionization Mass Spectrometric Analysis” J. Mass Spectrom. 56, 4 (SCI, IF=2.394)

  • Y. T. Cho, * H. Su, I. C. Huang, C. Y. Lai, Y. D. Tsai. 2019 “Rapid characterization of Organic UV Filters and their Photoproducts in Sunscreens by Thermal Desorption Electrospray Ionization Mass Spectrometry for the Photostability Study” Anal. Methods, 11, 6013–6022 (SCI, IF=3.532)

  • H. Su, M. Z. Huang, J. H. Chou, T. H. Chang, Y. M. Jiang, Y. T. Cho, S. C. Cheng, M. T. Wu, J. Shiea,* 2018 “High-Throughput Screening of Phthalate-Containing Objects in the Kindergartens by Ambient Mass Spectrometry” Anal. Chim. Acta,1039, 18, 65-73 (SCI, IF=6.991)

  •  S. C. Cheng, C. Shiea, Y. L. Huang, C. H. Wang, Y. T. Cho, J. Shiea. 2017 “Laser-Based Ambient Mass Spectrometry” Anal. Methods, 9, 34, 4924-4935 (SCI, IF=3.532)

  •  Y. T. Cho, H. Su, Y. Y. Chiang, J. Shiea,* S. S. F. Yuan, W. C. Hung, Y. T. Yeh, M. F. Hou. 2017 “Fine Needle Aspiration Combined with Matrix-Assisted Laser Desorption Ionization Time-of-Flight/Mass Spectrometry to Characterize Lipid Biomarkers for Diagnosing Accuracy of Breast Cancer” Clin. Breast Cancer 17, 5, 373–381.e1 (SCI, IF=3.078)

  • Y. T. Cho*, H. Su, S. J. Lin, B. H. Wu, C. Y. Lai, I. C. Huang. 2016 “Using Thermal Desorption Electrospray Ionization Mass Spectrometry to Rapidly Determine Antimicrobial Preservatives in Cosmetics” Rapid Commun. Mass Spectrom. 30, 21, 2315–2322 (SCI, IF=2.586)

  • Y. T. Cho, H. Su, W. J. Wu, D. C. Wu, M. F. Hou, C. H. Kuo, J. Shiea,*. 2015, “Biomarker Characterization by MALDI-TOF/MS” Adv. Clin. Chem. 69, 209-254 (SCI, IF=5.394)

  • Y. T. Cho, M. Z. Huang, S. Y. Wu, M. F. Hou, J. Li, J. Shiea. 2014, “Using Electrospray Laser Desorption Ionization Mass Spectrometry to Rapidly Examine the Integrity of Proteins Stored in Various Solutions” Anal. Bioanal. Chem. 406, 577-586 (SCI, IF=4.478)

  •  Y. T. Cho, C. H. Kuo, S. S.W. Wang, Y. S. Chen, B. C. Weng, Y. C. Lee, C. N. Cheng,  J. Shiea,* D. C. Wu. 2013, “Differentiation of Virulence of Helicobacter pylori by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Multivariate Analyses” Clin. Chim. Acta. 424, 123-130 (SCI, IF=6.314)

  • T. L. Huang, Y. T. Cho, H. Su, J. Shiea,* 2013, “Principle Component Analysis Combined with Matrix-Assisted Laser Desorption Ionization Mass Spectrometry for Rapid Diagnosing the Sera of Patients with Major Depression” Clin. Chim. Acta. 424, 175-181 (SCI, IF=6.314)

  • Y. T. Cho, C. W. Chen, M. P. Chen, J. L. Hu, J. Shiea, W. J. Wu, D, C, Wu. 2013, “Diagnosis of Albuminuria by Tryptic Digestion and Matrix-Assisted Laser Desorption Ionization/Time-of-Flight Mass Spectrometry” Clin. Chim. Acta. 420, 76-81 (SCI, IF=6.314)

  • Y. T. Cho, H. Su, T. L. Huang, H. C. Chen, W. J. Wu, P. C. Wu, D. C. Wu, J.  Shiea. 2013, “Matrix-Assisted Laser Desorption Ionization/Time-of-Flight Mass Spectrometry for Clinical Diagnosis” Clin. Chim. Acta. 415, 266-275 (SCI, IF=6.314)

  • C. C. Liu, C. F. Wu, J. Shiea, Y. T. Cho, Y. H. Chou, B. H. Chen, C. Y. Chien, S. P. Huang, W. J. Wu, J. T. Shen, M. Y. Chang, C. H. Huang, A. W. Chang, M. T. Wu. 2012, “Detection of Melamine in a Human Renal Uric Acid Stone by Matrix-Assisted Laser Desorption / Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS)” Clin. Chim. Acta. 413, 1689–1695 (SCI, IF=6.314)

  • Y. T. Cho, Y. Y. Chiang, J. Shiea, M. F. Hou, 2012, “Combining MALDI-TOF and molecular imaging with principal component analysis for biomarker discovery and clinical diagnosis of cancer” Genomic Medicine, Biomarkers, and Health Sciences. 4, 3-6

  • Y. T. Cho, Y. S. Chen, J. Shiea,* S. M. Yeh, H. C. Chen, Y. C. Lee, D. C. Wu, 2012, “The Study of Interferences for Diagnosing Albuminuria by Matrix-Assisted Laser Desorption Ionization/Time-of-Flight Mass Spectrometry” Clin. Chim. Acta. 413, 875–882 (SCI, IF=6.314)

  • M. Z. Huang, S. C. Cheng, Y. T. Cho, J. Shiea* 2011, “Ambient Ionization Mass Spectrometry - A Tutorial” Anal. Chim. Acta. 702,1-15 (SCI, IF=6.911)

  • M. Z. Huang, C. H. Yuan, S. C. Cheng, Y. T. Cho, J. Shiea.* 2010, “Ambient Ionization Mass Spectrometry” Annu. Rev. Anal. Chem. 3, 43–65 (SCI, IF=12.400)

  • J. Shiea,* Y. T. Cho, Y. S. Lin, C. W. Chang, L. H. Lo, Y. C. Lee, H. L. Ke, W. J. Wu, D. C. Wu, 2008, “Using Matrix-Assisted Laser Desorption Ionization/ Time-of-Flight Mass Spectrometry to Rapidly Screen for Albuminuria” Rapid Commun. Mass Spectrom. 22, 3754-3760 (SCI, IF=2.586)

  • Y. K. Li, H. J. Yao, Y. T. Cho, 2000, “Effective induction, purification and characterization of Trichoderma koningii G-39 -xylosidase with high transferase activity” Biotechnol Appl Biochem. 31, 119-25. (SCI, IF=2.724)

二、研究會論文

  • 卓怡「多變量統計析於質譜資料處理之應屆台灣質譜學會學術研討會暨2011年會 (論文) p276-286

一、研究案

  • 討- MOST 109-2637-M-514-001 -

  • 以貼仿究-科 MOST 106-2113-M-514-001-

  • 穿透影 MOST 105-2113-M-514-001-

  • 精油中含氧雜環化合物之檢測分析-110年度校內教師專題研究案 (110 S-01)

  • 精油中含氧雜環化合物之檢測分析-109年度校內教師專題研究案 (109 S-05)

  • 利用響-108年 (106 S-05)

  • 以熱灑游頭髮份-106年 (106 S-06)

  • 份-105年 (105 S-01)

  • 以質份-104 (104 S-01)

  • 以基爾蒙劑-102 (102 S-08)

二、改進教學案

  • ​​走進-103 (103 I-08)

  • 提高─參-102 (102 I-06)

專利

  • “Methods of Analyzing Peptide Mixtures” United States Patent. Patent No.: US 8,497,630 B2.

  • “Real-time monitor solid phase peptide synthesis by mass  spectrometry United States Patent. Patent No.: US 8,835,179 B2

  • 活體外檢測膀胱癌之法及系統 (METHOD FOR DETECTING BLADDER CANCER IN VITRO)中華民國明專專利 I487911

  • 「即時監測固相胜肽合反應之質譜系統中華民國發明專, 專利號:I510781

  • 「分析胜肽混合物之方」。中華民國發明專利,I613447

專書

  • 等合著 ( 105) 。化-基本概念應用。台北:華杏。

  • 丁望賢等合 ( 105) 。質分析技術原理與用。台北:全華。

  • 等合著 ( 102) 。化。台北:華杏。

  • 曹文正等合著 ( 100) 。新普通化學。台中:華格

  • 柯清彬等合著 ( 93) 。普通化學。中:華格那。

  • 王凱平等合 ( 91) 。化學台中:華格那。

​獎項及榮譽

  • 108 年度「優良教材具製作競賽」教材類優

  • 106 學年度教學評量優良教師。

  • 103 學年度教學優良師。

  • 102 學年度教學評量優良教師。

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  • ​​Oral Presentation:

  1. Yi-Tzu Cho, “Directly Characterizing Disease Biomarkers in Biofluids with Matrix-Assisted Laser Desorption Ionization/Time-of-Flight Mass Spectrometry” Mass Spectrometry for Clinical Diagnosis and Related Research Symposium (Nov 1-2, 2013, Kaohsiung, Taiwan)

  2. Yi-Tzu Cho, Jentaie Shiea* “Rapid Analysis of Bacteria and Fungi by Using Electrospray Laser Desorption (ELDI) Mass Spectrometry” 第八屆
    台灣質譜學會學術研討會暨2011質譜年會 (Jul 10-12, 2011)

  3. Yi-Tzu Cho, Jentaie Shiea* “Direct Characterization of the Proteins Stored in Solutions by Liquid Electrospray Laser Desorption Ionization
    (ELDI) Mass Spectrometry” 第 十 七 屆 分 析 化 學 技 術 交 流 研 討 會 . (May 14-15, 2011)

  4. Yi-Tzu Cho, Jentaie Shiea,* “Using MALDI/TOF to Characterize Carcinogenicity of Helicobacter Pylori Strain” 
    2010台灣質譜學會第七屆學術研討會 (Jun 27-29, 2010)

  5. Yi-Tzu Cho, Jentaie Shiea,* “On-line HPLC with H/D Exchange in Liquid Electrospray-Assisted Laser Desorption Ionization Mass Spectrometry for The Analysis of Protein Mixture ”
    第十五屆分析化學技術交流研討會. (May 16, 2009)

  • Poster Presentation:

  1. Yi-Tzu Cho, *Shu-Qing Liu, Ching-Fang Chang and Li-Xiang Zhao “The Study of the Photoreactions of the Combination of Organic UV-filters” 2021 化學年會 (Mar . 12-14, 2021, Taoyuan, Taiwan)

  2. Yi-Tzu Cho, * Hung Su, Chia-Wei Liu, Wei-Ling Chen, Yu-Han Hong “Detection of Oxygenated Heterocyclic Compounds in Essential Oils”2020 年第十七屆台灣質譜學會年會 17th Annual Conference of the Taiwan Society for Mass Spectrometry, (Sep. 1-3, 2020, Chiayi, Taiwan)

  3. 翁華均,方祺圍,張家琦,蘇鴻,陳婉瑩,江郁旻,卓怡孜,* “仿曬劑之梅納反應的作用探討” 第十五屆台灣質譜學會年會暨第七屆世界華人質譜研討會 15th TSMS Annual Conference & 7th World Chinese Mass Spectrometry Conference (Jul 18-20, 2018, Taipei, Taiwan)

  4. Yi-Tzu Cho, * Hung Su, I-Ching Huang, Ching-Yu Lai, You-Da Tsai. “Using Thermal Desorption Electrospray Ionization Mass Spectrometry to Study Photostability of Organic UV-Filters” 2017中國化學年會 (Dec 01-02, 2017, Chiayi, Taiwan)

  5. Yi-Tzu Cho, Hung Su, Jia-Ming Lin, Yang-Kuan Pan, Yu-Hsuan Kuo, Jentaie Shiea,* “Whole-Body Imaging of Sebaceous Squalene by Ambient Mass Spectrometry” 2017 Mass Spectrometry for Clinical Diagnosis Conference (MSCD 2017) (Oct 13-15, 2017, Kaohsiung, Taiwan)

  6. Jentaie Shiea, Hung Su, Yu-Hsuan Kuo, Yang-Kuan Pan, Yi-Tzu Cho,* “Imaging of Sebaceous Cholesterol on Human Face by In-situ Probe Sampling and Thermal Desorption Electrospray Ionization Mass Spectrometry” 2017 Mass Spectrometry for Clinical Diagnosis Conference (MSCD 2017) (Oct 13-15, 2017, Kaohsiung, Taiwan)

  7. Yi-Tzu Cho, Hung Su, Yi-Yan Chiang, Jentaie Shiea, Shyng-Shiou F. Yuan, Wen-Chun Hung, Yao-TsungYeh, Ming-Feng Hou* “Fine Needle Aspiration Combined with Matrix-Assisted Laser Desorption Ionization Time-of-Flight/Mass Spectrometry to Characterize Lipid Biomarkers for Diagnosing Accuracy of Breast Cancer” 2017 Mass Spectrometry for Clinical Diagnosis Conference (MSCD 2017) (Oct 13-15, 2017, Kaohsiung, Taiwan)

  8. 黃薏靜,賴謦妤,謝承芳,陳芃芸,黃雅慈,李雨樺,卓怡孜* “以現代質譜法及紫外線光譜法進行防曬劑光穩定性探討” 第十四屆台灣質譜學會年會暨2017年學術研討會 14 th Annual Conference of the Taiwan Society for Mass Spectrometry (Jun 28-30, 2017, Taichung, Taiwan)

  9. 李家妘,楊卉蘋,蔡忻慈,林芷璇,陳孟琳,柳俐安,林欣怡,李宜庭,卓怡孜* “以質譜法及防曬係數測定法進行不同劑型防曬品之光穩定性探討” 第十四屆台灣質譜學會年會暨2017年學術研討會 14 th Annual Conference of the Taiwan Society for Mass Spectrometry (Jun 28-30, 2017, Taichung, Taiwan)

  10. 趙雅馨,黃姿寧,蕭郁萱,邱芊慈,張簡郁軒,林妤芝,陳姵妤,卓怡孜*  “以貼布剝離法結合大氣壓力游離質譜法進行防曬品之經皮穿透探討” 第十四屆台灣質譜學會年會暨2017年學術研討會 14 th Annual Conference of the Taiwan Society for Mass Spectrometry (Jun 28-30, 2017, Taichung, Taiwan)

  11. Yi-Tzu Cho,* Hung Su, Shiang-Jiun Lin, Zing-Rong Chen, Yu-Jiy Lin, Pen-Yun Chen, Jentaie Shiea* “Monitoring the Residual of Risky Cosmetics Ingredients on the Human Body by in-situ Sampling and TD-ESI/MS” 13th Taiwan Society for Mass Spectrometry Annual Conference(July 27-29, 2016, Kaohsiung, Taiwan)

  12. 郭育萱,蘇鴻,謝建台,黃薏靜,賴謦妤, 謝承芳,黃雅慈,卓怡孜* “熱脫附電噴灑游離質譜法快速檢測市售化妝品中的美白成份”13th Taiwan Society for Mass Spectrometry Annual Conference(July 27-29, 2016, Kaohsiung, Taiwan)

  13. Yi-Tzu Cho,,* Ban-Hsin Wu,2 Hung Su, Shiang Jiun Lin, Jentaie Shiea “Using Thermal Desorption Electrospray Ionization Mass Spectrometry to Rapidly Determine Antimicrobial Preservatives in Cosmetics” 12th Taiwan Society for Mass Spectrometry Annual Conference(July 13-15, 2015, Hsinchu, Taiwan)

  14. Yi-Tzu Cho, * Ban-Hsin Wu, Hung Su, Jentaie Shiea* “TD-ESI/MS and MALDI-TOF/MS for Rapid Characterization of Cosmetic Products” (Jun 29- Jul 1, 2014, Taichung, Taiwan)

  15. Yi-Tzu Cho, Jentaie Shiea* “Semi-Quantitative Diagnoses of Albuminuria by MALDI-TOF Mass Spectrometry” 4th Asia Oceania Mass Spectrometry Conference & 10th Taiwan Society for Mass Spectrometry Annual Conference  (Jul 10-12, 2013, Taipei, Taiwan)

  16. Yi-Tzu Cho, Chu-Nian Cheng, Hung Su , Jentaie Shiea* “Using Thin Layer Chromatography Spray (TLC spray) Ionization Mass Spectrometry to Analyze Drugs in Whole Blood” 19th International Mass Spectrometry Conference (Sep 15-21, 2012, Kyoto, Japan)

  17. Yi-Tzu Cho, Yi-Yan Chiang, Jentaie Shiea, * Pei-Yung Nien, Yia-Fung Huang,  Ming-Feng, Hou, “Using MALDI-TOF/MS Combined with Molecular Imaging for Breast Cancer Diagnosis” (Sep 30- Oct 1, 2011, Kaohsiung, Taiwan)

  18. Yi-Tzu Cho, Jentaie Shiea* “Rapid Characterization of the Proteins Stored in Various Solutions by Liquid Electrospray Laser Desorption Ionization (ELDI) Mass Spectrometry” The 2nd Asin & Oceanic Mass Spectrometry Conference (Aug 17-19, 2011, Busan, Korea)

  19. Yi-Tzu Cho, Jentaie Shiea* “Direct Characterization of the Proteins Stored in Solutions by Liquid Electrospray Laser Desorption Ionization (ELDI) Mass Spectrometry” The 59th ASMS Conference on Mass Spectrometry. (Jun 05-09, 2011)

  20. Yi-Tzu Cho, Jentaie Shiea* “Direct Characterization of the Proteins Stored in Solutions by Liquid Electrospray Laser Desorption Ionization (ELDI) Mass Spectrometry” 2011 Taiwan –Russia Research Cooperation symposium (Apr 25-26, 2011)

  21. Yi-Tzu Cho, Jentaie Shiea* “Using Matrix-assisted Laser Desorption Ionization Mass Spectrometry Combined with Statistical Software to Rapidly Diagnose Albuminuria” 2009中國化學年會. (Dec 03-05, 2010)

  22. Yi-Tzu Cho, Yu-Syuan Chen, Yi-Yan Chiang, Jentaie Shiea,* “Using MALDI-TOF MS Combined with multivariate Statistics to Classify ER and HER2 Status in Breast Cancer Cell Lines” 2010 Kaohsiung International Cancer Symposium. (Nov 20-21, 2010)

  23. Yi-Tzu Cho, Jentaie Shiea* “Determination of Rapid H/D Exchange Number of Proteins in different pH by Electrospray Laser Desorption Ionization (ELDI)” The 1st Asian and Oceanic Mass Spectrometry Conference. (Jun 15-18, 2010)

  24. Yi-Tzu Cho, Jentaie Shiea* “Examination of the Protein Molecules Stored in Various Solutions by Liquid Electrospray Laser  Desorption/Ionization (ELDI) Mass Spectrometry” 2009中國化學年會. (Dec 04-06, 2009)

  25. Yi-Tzu Cho, Jentaie Shiea* “Detection of H/D and D/H Exchange of Proteins in Solid and Liquid States by Electrospray-Assisted Laser Desorption Ionization (ELDI) Mass Spectrometry”第六屆物理與化學女性學者聯合研討會 (Oct 31-Nov 01, 2009)

  26. Yi-Tzu Cho, Jentaie Shiea,* “On-line H/D Exchange for the Analysis of Protein Mixture using HPLC combined with Electrospray-Assisted Laser Desorption Ionization Mass Spectrometry” 18th International Mass Spectrometry Conference. (Aug30-Sep 04, 2009)

  27. Yi-Tzu Cho, Jentaie Shiea,* “On-line HPLC with H/D Exchange in Liquid Electrospray-Assisted Laser Desorption Ionization Mass Spectrometry for The Analysis of Protein Mixture” 台灣質譜學會學術研討會暨2009質譜年會. (Dec 13, 2009)

  28. Yi-Tzu Cho, Jingyueh Jeng, Jentaie Shiea,* “On-line HPLC with H/D Exchangein Liquid Electrospray-Assisted Laser Desorption Ionization Mass Spectrometry for the Analysis of Protein Mixture” The 57th ASMS Conference on MassSpectrometry. (May 31-Jun 4, 2009)

  29. Yi-Tzu Cho, Min-Zong  Huang,  Li-Jie  Wu,  Yu-Syuan  Chen, Jentaie Shiea,*Rapid Drug Tablets Analysis by Electrospray-assisted Laser Desorption Ionization (ELDI)Mass Spectrometry”2008中國化學年會. (Dec 05-07, 2008)

  30. Yi-Tzu Cho, Jentaie  Shiea,* “Rapid Detection of Albumin in Urine by Matrix-Assisted Laser Desorption  Ionization/Time-of-Flight Mass Spectrometry”2008台北國際分析化學會議 (2008 ICCT:  Analytical Chemistry). (Oct 02-05,2008)

  31. Yi-Tzu Cho, Che-Hsin Lin, Jentaie Shiea,* “Direct Analysis in Real Time/Mass Spectrometry for Continuously Monitoring the States of  Ongoing Chemical Reactions Involved with Volatile Compounds”第二屆世界華人質譜研討會暨 2008台灣質譜年會. (Jun 26-27, 2008)

  32. Yi-Tzu Cho, Che-Hsin Lin, Jentaie Shiea,* “Direct Analysis in Real Time/Mass Spectrometry for Continuously Monitoring the States of Ongoing Chemical Reactions Involved with Volatile Compounds” The 56th ASMS Conference on Mass Spectrometry. (Jun 1-5, 2008)

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