最高學歷：高雄醫學大學藥學系博士

專長：藥物學、老人學、基礎醫學、營養學

授課科目：藥物學、老人學、高齡保健與膳食營養、病理學

電話分機：1130

電子信箱：a0338@ms.yuhing.edu.tw

高雄醫學大學藥學系博士

義守大學生物技術與化學工程研究所碩士

弘光科技大學食品營養系學士

1.育英醫護管理專科學校老人服務事業管理科助理教授

2.育英醫護管理專科學校技術合作處綜合規劃組組長

3.成功大學產學創新總中心博士後研究員

4.義守大學學士後中醫學系兼任助理教授

5.慈惠醫護管理專科學校護理科兼任講師

藥物學、老人學、基礎醫學、營養學

1.居家服務督導員

2.行政院勞工委員會中餐烹調丙級技術士

3.行政院勞工委員會烘焙食品(麵包)丙級技術士

期刊論文

1.Ching-chung Tsai, S. Tey, M. Lee, Ching-Wen Liu, Yu-Tsun Su, S. Huang, "Mechanism of resveratrol-induced relaxation of the guinea pig fundus", Phytomedicine, vol. 43, pp. 55-59, 2018.0 國際期刊SCI, Impact Factor: 4.18, Rank Factor: 1/27. Subject Categories: INTEGRATIVE & COMPLEMENTARY MEDICINE

2. Cheng-Tse Lee, Li-Ching Chang, Ching-Wen Liu, Pei-Fung Wu, "Negative correlation between serum uric acid and kidney URAT1 mRNA expression caused by resveratrol in rats", Molecular Nutrition & Food Research, vol. 61, no. 10, pp. 1-10, 2017.10. 國際期刊 SCI, Impact Factor:4.323, Rank Factor: 7/130. Subject Categories: FOOD SCIENCE & TECHNOLOGY

3. Ching-Chung Tsai, Ming-Che Lee, Shu-Leei Tey, Ching-Wen Liu, Shih-Che Huang, "Mechanism of resveratrol-induced relaxation in the human gallbladder", BMC Complement Altern Med, no. 17:254, 2017.05 國際期刊SCI, Impact Factor: 2.833, Rank Factor: 6/28. Subject Categories: MEDICINE

4. Ching-Wen Liu, Yu-Tse Wu, Kai-Jen Lin, Tsan-Jung Yu, Yu-Liang Kuo, Li-Ching Chang, "A Hydrogel-Based Epirubicin Delivery System for Intravesical Chemotherapy", Molecules, vol. 21, no. 6, pp. 712-729, 2016.06. 國際期刊SCI, Impact Factor: 2.465, Rank Factor: 24/59. Subject Categories: CHEMISTRY, ORGANIC

5. Ching-Chung Tsai, Li-Ching Chang, Kai-Jen Lin, Shu-Leei Tey, YuTsun Su, Ching-Wen Liu, Tong-Rong Tsai, Shih-Che Huang, "Mechanism of bombesin-induced tonic contraction of the porcine lower esophageal sphincter", Scientific Reports, vol. 5, pp. 15879, 2015.1.國際期刊 SCI, Impact Factor: 5.578, Rank Factor: 5/57. Subject Categories: MULTIDISCIPLINARY SCIENCES

6. Ching-Chung Tsai, Li-Ching Chang, Shih-Che Huan, Shu-Leei Tey, Wen-Li Hsu, Yu-Tsun Su, Ching-Wen Liu, Tong-Rong Tsai, "Salvia miltiorrhiza Induces Tonic Contraction of the Lower Esophageal Sphincter in Rats via Activation of Extracellular Ca2 + Influx", Molecules, vol. 20, no. 8, pp. 14504-14521, 2015.08. 國際期刊SCI, Impact Factor: 2.416, Rank Factor: 22/58. Subject Categories: CHEMISTRY, ORGANIC

7. Pei-Fung Wu, Yaw-Sen Chen, Ting-Yin Kuo, Hsi-Hsun Lin, Ching-Wen Liu, Li-Ching Chang, "APOBEC3B: A Potential Factor Suppressing Growth of Human Hepatocellular Carcinoma Cells", Anticancer Research, vol. 35, no. 3, pp. 1521-1527, 2015.03. 國 際 期 刊 SCI, Impact Factor: 1.826, Rank Factor: 162/211. Subject Categories: ONCOLOGY

8. Ching-Wen Liu, Li-Ching Chang, Kai-Jen Lin, Tsan-Jung Yu, Ching-Chung Tsai, Hao-Kuang Wang, Tong-Rong Tsai, "Preparation and characterization of gelatin-based mucoadhesive nanocomposites as intravesical gene delivery scaffolds", BioMed Research International (formerly titled Journal of Biomedicine and Biotechnology) , vol. 2014, no. 12, pp. 1-12, 2014.12. 國際期刊 SCI, Impact Factor: 2.706, Rank Factor: 53/165. Subject Categories: BIOTECHNOLOGY & APPLIED MICROBIOLOGY

9. Li-Ching Chang, Ting-Yin, Kuo, Ching-Wen Liu, Yaw-Sen Chen, Hsi-Hsun Lin, Pei-Fung Wu, "APOBEC3G exerts tumor suppressive effects in human hepatocellular carcinoma", Anticancer drugs, vol. 25, no. 4, pp. 456-461, 2014.04. 國際期刊 SCI, Impact Factor: 1.891, Rank Factor: 155/254. Subject Categories: PHARMACOLOGY & PHARMACY.

10. Li-Ching Chang, Chun-Jen Cheng, Tung-Hu Tsai, Ching-Wen Liu, Tong-Rong Tsai, "Optimization of rate-controlled 17beta-estradiol nanoparticles for cerebral ischemia therapy", Journal of Biomedical Nanotechnology, vol. 9, no. 10, pp. 1724-1735, 2013.10. 國際期刊SCI, Impact Factor: 5.256, Rank Factor: 16/121. Subject Categories: MEDICINE, RESEARCH & EXPERIMENTA.

11. Ching-Chung Tsai, Shih-Che Huang, Jong-Kang Liu, Hsiu-Chuan Wang, Tong-Rong Tsai, Ping-Ju Tsai, Ching-Wen Liu, Li-Ching Chang, "Salvia miltiorrhiza causes tonic contraction in rat ileum through Ca2+-calmodulin pathway", Journal of Ethnopharmacology, vol. 142, no. 3, pp. 694-699, 2012.08. 國際期刊 SCI, Impact Factor: 3.014, Rank Factor: 31/190. Subject Categories: PLANT SCIENCES

12. Fan-Yun Mong, Yu-Liang Kuo, Ching-Wen Liu, Wen-Sheng Liu, Li-Ching Chang, "Association of gene polymorphisms in prolactin and its receptor with breast cancer risk in Taiwanese women", Molecular Biology Reports, vol. 38, no. 7, pp. 4629-4636,2011.10. 國際期刊SCI, Impact Factor: 2.929, Rank Factor: 135/289. Subject Categories: BIOCHEMISTRY & MOLECULAR BIOLOGY

研討會論文

1.Ching-Wen Liu, Ming-Yue Wang, Pei-Fung Wu, Yi-Ping Hsiang, Tsan-Jung Yu, Li-Ching Chang, "Application of nanohydrogels as gene delivery scaffolds to induce bladder tumor senescence", The 44th Annual Meeting of the Molecular Biology Society of Japan, pp.3P-0340, Yokohama, Japan, 2021.12 國際性研討會

2.Pei-Fung Wu, Ching-Wen Liu, Yu-Fen Hung, Tsan-Jung Yu, LiChing Chang*. Effective scaffolds for lentiviral transduction in intravesical gene delivery. The 42nd Annual Meeting of the Molecular Biology Society of Japan, pp.4P-0014, Fukuoka, Japan, 2019.12 國際性研討會

3.Ching-Wen Liu, Yu-Fen Hung, Tsan-Jung Yu, Li-Ching Chang*. Nano-formulated Scaffold for Intravesical Gene Delivery by Targeting Microenvironment of Bladder Cancer. 2019 Controlled Release Society (CRS) Annual Meeting, Valencia, Spain, 2019.07. 國際性研討會

4.Ching-Wen Liu, Yu-Fen Hung, Tsan-Jung Yu, Li-Ching Chang*. Nano-formulated Scaffold for Intravesical Gene Delivery by Targeting Microenvironment of Bladder Cancer. 2019 Controlled Release Society (CRS) Annual Meeting, Valencia, Spain, 2019.07. 國際性研討會

5.Ching-Chung Tsai, Ching-Wen Liu, Yu-Fen Hung, Li-Ching Chang* Influences of Tanshinone IIA on Calcium Wave in the Lower Esophageal Sphincter Cells. The 33th Joint Annual Conference of Biomedical Sciences (2018), pp.BC174, Taipei, 2018.03. 國際性研討會

6.Tsan-Jung Yu, Ching-Wen Liu, Yu-Fen Hung, Li-Ching Chang*. The Effect of V-ATPase Overexpression on Autophagy of Bladder Cancer Cells. The 33th Joint Annual Conference of Biomedical Sciences (2018), pp.BC177, Taipei, 2018.03. 國際性研討會

7. Pei-Fung Wu, Ching-Wen Liu, Yu-Hsuan Yen, Li-Ching Chang*. Study the regulation of lipoic acid in LPS-induced IL-6 expression in C2C12 myotube. 第 40 回日本分子生物學會年會, pp.2P-0322, 日本神戶, 2017.12. 國際性研討會

8. Ching-Wen Liu, Wen-Teng Chang, Pei-Fung Wu, Yu-Hsuan Yen, Yu-Fen Hung, Li-Ching Chang*. Biomarkers of Senescent Cells. 2017 學術研討會-健康醫療產業於老化醫學的應用趨勢, pp.S-B 01, Tainan, 2017.03. 國際性研討會

9. Wen-Teng Chang, Ching-Wen Liu, Pei-Fung Wu, Yu-Hsuan Ye, YuFen Hung, Li-Ching Chang, "Current Trends in Anti-aging Drug Development", 2017 學術研討會-健康醫療產業於老化醫學的應用趨勢, pp.S-B 02, Tainan, 2017.03. 國際性研討會

產學合作案

1.樂齡取代餐料理包

2.110年深耕計畫3-1-2健康促進支持服務

個人專利

1. 鋁擠型冰包結構(新型M603467)

2. 3D細胞培養膠體的套組及其用於3D細胞培養的方法(發明I746069)